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Est indicado para el tratamiento de adultos con diabetes mellitus tipo 2 insuficientemente controlada, para mejorar el control glucmico como complemento de la dieta y el ejercicio

A peptide GLP-1 needs solid-phase synthesis (semaglutide is a 31-mer with non-natural modifications and a lipid chain) or recombinant expression followed by complex modification

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Untested formulations Semaglutide and tirzepatide are FDA-approved as injectables (an oral tablet version of semaglutide is also approved), but the formulations some drug compounding pharmacies are selling in the form of sublingual drops or dissolving tablets have never been studied in clinical trials